歌礼制药-B(01672)：ASC41片治疗经肝穿活检证实的非酒精性脂肪性肝炎患者52周II期临床试验取得积极期中结果
歌礼制药-B(01672)公布，公司全资附属公司甘莱制药有限公司的候选药物甲状腺激素受体β(THRβ)激动剂ASC41片用于治疗经肝穿活检证实的非酒精性脂肪性肝炎(NASH)患者的52周II期临床试验取得积极期中结果。ASC41 具有肝脏靶向性和高度的THRβ选择性。一日服用一次的ASC41片剂由歌礼专有制剂技术开发。ASC41片剂制剂专利已在美国获得授权。
该项随机、双盲、安慰剂对照及多中心的II期临床试验(ClinicalTrials.gov : NCT05462353) 正在中国开展，预计入组约180名经肝穿活检证实的NASH患者，以1:1:1的比例随机分配进入两个ASC41片治疗队列(2毫克或4毫克，一日一次)和一个安慰剂对照队列，治疗52周并随访4周。预设的期中分析在42名入组患者完成为期12周的 ASC41片或安慰剂治疗后进行。
Reprinted from 引领外汇网，the copyright all reserved by the original author.
Disclaimer: The content above represents only the views of the author or guest. It does not represent any views or positions of FOLLOWME and does not mean that FOLLOWME agrees with its statement or description, nor does it constitute any investment advice. For all actions taken by visitors based on information provided by the FOLLOWME community, the community does not assume any form of liability unless otherwise expressly promised in writing.
FOLLOWME Trading Community Website: https://www.followme.com
Hot
No comment on record. Start new comment.