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最新研究揭示新冠病毒高传染性新机制,或提供新的抗病毒靶点

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高传染性是新冠病毒(SARS-CoV-2)的特点之一,也对疫情大防控带来极大的挑战。这种高传染性背后的机制是什么?洛桑联邦理工学院(EPFL)的研究团队在国际学术期刊Cell子刊Developmental Cell发表了一项最新研究,提出了新的见解。
和许多其他的病毒一样,SARS-CoV-2依赖宿主酶携带的脂质修饰来组织细胞膜结构,从而协调毒力蛋白的功能。洛桑联邦理工学院的研究团队在这项最新的研究中发现了将脂肪酸转移到SARS-CoV-2主要成分融合蛋白Spike上的酶。这项突破性研究表明,这些脂肪酸对SARS-CoV-2的传染性非常重要,并有助于开发治疗冠状病毒和其他例如疱疹和流感病毒的新药。

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